Francesco Chiappelli, PhD


Title:  Implications and Applications of Evidence-Based Research in Evidence-Based Dental Practice


Synopsis:  Prosthodontics is fast advancing in the new era of evidence-based clinical decision-making and practice.  This model of dentistry, which was first defined by ADA a decade ago, is grounded on three fundamental steps, which entail the synthesis of the available evidence, the evaluation of the resulting revisions in clinical practice guidelines, and the integration of this consensus of the research evidence with the dentist's expertise, the patient's wants & needs, and with economic (insurance coverage vs. private payment) and ethical factors (i.e., cost/risk & cost/benefit estimates).  The goal of evidence-based practice in prosthodontics is to ensure the utilization of the best available evidence and knowledge in treatment modalities for optimizing benefit to our patient.  We will examine these facets of evidence-based prosthodontics, peruse concepts and policies, and discuss specific examples, and recently published materials by our research group and others.


Course Objectives:

1.    Distinguishing traditional dentistry based on the evidence and the newly emerged model for XXI century of dentistry, evidence-based dentistry

2.    Distinguishing between assessment of research literature based on the levels of evidence, or based on research evaluative criteria

3.    Distinguishing literature reviews, from best-case reviews, from systematic reviews, and identifying the criteria that dictate incorporation of systematic findings into evidence-based dental practice

4.    Distinguishing the normative determinants of evidence-based clinical decision making toward treatment-effective, and patient utility-effective intervention


References:  Four references have been supplied that reflect the content of Dr. Chiappelli’s presentation.

Evidence-based Research in Complementary and

Alternative Medicine I: History

Francesco Chiappelli, Paolo Prolo, and Olivia S. Cajulis

Evidence-Based Research in Complementary and Alternative

Medicine II: The Process of Evidence-Based Research

Francesco Chiappelli, Paolo Prolo,  Monica Rosenblum,

Myeshia Edgerton, and Olivia S. Cajulis

Evidence-Based Research in Complementary and Alternative

Medicine III: Treatment of Patients with Alzheimer’s Disease

Francesco Chiappelli,  Audrey M. Navarro,  David R. Moradi, Ercolano Manfrini and

Paolo Prolo.

Model of Evidence-Based Dental Decision Making

Janet Bauer, Sue Spackman, Francesco Chiappelli, Paolo Prolo, MD


Bio: Professor Chiappelli left 1st year Medical School in Bologna, Italy to come to UCLA in the early 1970's.  There, he obtained his Bachelor's, Master's and PhD degrees.  He stayed at UCLA for a joint NIAID/Norman Cousins post-doctoral fellowship, followed by two years of research specialization in Biological Psychiatry at Harbor-UCLA Medical Center.  By the early 1990's, Dr. Chiappelli established his research laboratory in human fundamental immunology and psychoneuroimmunology on the grounds of the West Los Angeles Veterans Administration Medical Center.  In the mid 1990's, Dr. Chiappelli joined the faculty of the School of Dentistry at UCLA, where his initial teaching assignment entailed biostatistics and research designs.  He soon transformed these two dental courses into Evidence-Based Dentistry I & II for first and second year dental students in a timeline that coincided with the 1999 ADA statement on Evidence-Based Dentistry.  Within a few years, Dr. Chiappelli established a graduate course in evidence-based dentistry, a requirement for the master's program in Oral Biology at UCLA.  Similarly, he endeavored in teaching CE evidence-based dentistry courses at UCLA, throughout California, and internationally as far as Brazil (2009).  Since 2005, Dr. Chiappelli has introduced the field of evidence-based research in dentistry and evidence-based clinical decision-making in dentistry to undergraduate pre-dental students at UCLA as well.  His textbook on evidence-based research and its applications and implications to the clinical health sciences, including dentistry, has now become available through Nova Publisher.  He currently continues his research in evidence-based dentistry, guides graduate students in their thesis work in the field, publishes and serves on the editorial board of several national and international journals that pertain to evidence-based research and decision-making, and contributes book chapters on the topic of evidence-based dental care.  Professor Chiappelli is currently completing a monograph on evidence-based clinical decision-making for sustainable solutions to be published by Nova later this year.